Ladue began as a farming community in St. Louis County. Once automobiles replaced horse and wagon as the primary mode of transportation, farmers in the area began selling portions of their land to city workers who wished to live outside of the urban setting. Three small villages (Village of LaDue, Village of Deer Creek, and the Village of McKnight) merged in 1936 to become what is now known as Ladue.
Ladue is an inner-ring suburb of St. Louis, located in St. Louis County, Missouri. As of the 2020 census, the city had a population of 8,989. Ladue has the highest median household income of any city in Missouri with a population over 1,000.